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14 cards ranked

Best credit card to use at Duane Reade.

Drugstore

Duane Reade is the New York City banner of Walgreens, with roughly 250 locations concentrated in the five boroughs and surrounding suburbs. The format is essentially a Walgreens drugstore adapted to dense urban real estate, often with a heavier prepared food and convenience selection. Duane Reade codes as a drugstore, so any drugstore category bonus card (Amex Blue Cash Preferred, Citi Custom Cash on drugstores) will earn its full multiplier. The myWalgreens loyalty program works at Duane Reade registers as well.

  1. #1
    Citi Custom Cashif it’s your top category
    Citi
    5% on drugstores if it's your top eligible spend category that cycle (up to $500/month, then 1%)
    Automatically on your top eligible spend category each billing cycle
    5%
  2. #2
    AAA Daily Advantage Visa Signature
    Comenity Capital Bank
    3% on drugstores
    Pharmacy purchases
    3%
  3. #3
    Chase Freedom Flex
    Chase
    3% on drugstores
    3%
  4. #4
    Chase Freedom Unlimited
    Chase
    3% on drugstores
    3%
  5. #5
    Venmo Credit Cardif it’s your top category
    Synchrony
    3% on drugstores if it's your top eligible spend category that cycle
    Automatically on your highest-spend eligible category each statement period (8 eligible: transportation, travel, groceries, entertainment, dining & nightlife, bills & utilities, health & beauty, gas). Drugstores here represents health & beauty; bills & utilities maps to utilities.
    3%
  6. #6
    Robinhood Gold
    Robinhood
    3% flat-rate cashback
    3%
  7. #7
    Blue Business Cash from American Express
    American Express
    2% flat-rate cashback
    2%
  8. #8
    Citi Double Cash
    Citi
    2% flat-rate cashback
    1% when you buy, 1% when you pay
    2%
  9. #9
    Coinbase One
    First Electronic Bank
    2% flat-rate cashback
    Up to 4% with higher crypto balances on Coinbase; requires Coinbase One membership
    2%
  10. #10
    Fidelity Rewards Visa Signature
    Elan Financial Services
    2% flat-rate cashback
    When deposited into an eligible Fidelity account
    2%
  11. #11
    Graphite Business Cash Unlimited
    American Express
    2% flat-rate cashback
    Unlimited 2% cash back on eligible purchases
    2%
  12. #12
    Smartly Visa Signature
    U.S. Bank
    2% flat-rate cashback
    2%
  13. #13
    Wells Fargo Active Cash
    Wells Fargo
    2% flat-rate cashback
    2%
  14. #14
    Wells Fargo Signify Business Cash
    Wells Fargo
    2% flat-rate cashback
    2%

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Last updated May 17, 2026

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